Crinone contains a hormone called progesterone. When the gel is inserted into your vagina, theprogesterone is slowly released into your bloodstream throughout the day.Crinone is used to give you extra progesterone in the treatment of infertility due to incorrect levels ofprogesterone during the menstrual cycle or when you are having an assisted fertility procedure. This is tohelp you get pregnant. You may also be asked to continue using Crinone to support your new pregnancy