Lansoprazole is a medication that is used for multiple indications in adults: Duodenal ulcers (sore that forms at the beginning of your small intestine) H Pylori eradication (a bacteria that can live in your gut and cause ulcers) to prevent recurrence of duodenal ulcers Benign gastric ulcer (non-cancerous sore that forms in your stomach) NSAID-associated ulcer (sore that forms in your gut due to excessive use of NSAIDs) GERD (acid reflux also known as “heartburn”) In addition, it can be used in children for the following indications: GERD Erosive esophagitis (acid irritation injuring the esophagus)